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mfe Δ is the energy difference from the best reported interaction for the same query–target pair; in evaluation, the reference is the best supplied structure. It is not a free-energy change. Coordinates are inclusive and use your start indices. Table visibility does not change the selected CSV download columns.
Interaction visualization
Open in vaRRISelect View on an interaction to visualize it.
Selecting View loads vaRRI with that sequence pair and structure in its URL.
Show or hide mutation columns
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Ranks and scores follow the selected CopomuS measures. NA denotes an unavailable interaction or profile score.
Compensatory-mutation visualization
Open in vaRRISelect View on a mutation to inspect its annotated interaction and energy states.
vaRRI shows the wild-type interaction with the designed query and target substitutions annotated in dark green. The chart compares the wild-type, single-mutant and compensatory energies.